Overview

  • Product name

  • Description

    Rabbit polyclonal to FFAR3/GPR41
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human FFAR3/GPR41 (internal sequence).
    Database link: NP_005295.1

  • Positive control

    • Human liver and Human adrenal tissues
  • General notes

     This product was previously labelled as FFAR3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab150483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Requires pretreatment with Proteinase K.

Target

  • Function

    Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.
  • Tissue specificity

    Highest level in adipose tissue, and lower expression across all tissues tested.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FFA3R antibody
    • Ffar3 antibody
    • FFAR3_HUMAN antibody
    • Free fatty acid receptor 3 antibody
    • G protein coupled receptor 41 antibody
    • G-protein coupled receptor 41 antibody
    • gpcr41 antibody
    • GPR41 antibody
    • gpr42 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human liver tissue labelling FFAR3/GPR41 with ab150483 antibody at a concentration of 5 µg/ml.

  • Immunohistochemical analysis of paraffin embedded Human adrenal tissue labelling FFAR3/GPR41 with ab150483 antibody at a concentration of 5 µg/ml.

References

ab150483 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab150483.
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