Key features and details
- Novel and highly fluorescent VMAT2 substrate
- CAS Number: 1447064-50-7
- Purity: > 95%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameFFN206, fluorescent VMAT2 substrate
DescriptionNovel and highly fluorescent VMAT2 substrate
Novel and highly fluorescent VMAT2 substrate. Enables quantitative and high throughput examination of VMAT2. Detects VMAT2 activity in intact cells (Km = 1.16 µM). Allows optical examination of VMAT2 function in cell culture.
Chemical name4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one trifluoroacetate
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144554 has been referenced in 2 publications.
- Iannielli A et al. Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses. Cell Rep 29:4646-4656.e4 (2019). PubMed: 31875567
- Liu S et al. Zoledronate modulates intracellular vesicle trafficking in mast cells via disturbing the interaction of myosinVa/Rab3a and sytaxin4/VAMP7. Biochem Pharmacol 151:18-25 (2018). PubMed: 29454616