Overview

  • Product name
    Anti-FGD3 antibody [EPR12448] - BSA and Azide free
    See all FGD3 primary antibodies
  • Description
    Rabbit monoclonal [EPR12448] to FGD3 - BSA and Azide free
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cyt, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Orangutan
  • Immunogen

    Synthetic peptide within Human FGD3 aa 100-200 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q5JSP0

  • General notes

    ab249843 is a PBS-only buffer format of ab174857. Please refer to ab174857 for recommended dilutions, protocols, and image data.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab249843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 79 kDa.
Flow Cyt Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
    • Sequence similarities
      Contains 1 DH (DBL-homology) domain.
      Contains 1 FYVE-type zinc finger.
      Contains 2 PH domains.
    • Cellular localization
      Cytoplasm. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • Faciogenital dysplasia 3 antibody
      • FGD1 family, member 3 antibody
      • FGD3 antibody
      • FGD3_HUMAN antibody
      • FYVE antibody
      • FYVE, RhoGEF and PH domain containing 3 antibody
      • FYVE, RhoGEF and PH domain containing protein 3 antibody
      • RhoGEF and PH domain-containing protein 3 antibody
      • ZFYVE5 antibody
      • Zinc finger FYVE domain containing protein 5 antibody
      • Zinc finger FYVE domain-containing protein 5 antibody
      see all

    References

    ab249843 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab249843.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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