Overview

  • Product name

  • Description

    Rabbit polyclonal to FGF17
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human FGF17 aa 25-51.
    Sequence:

    GENHPSPNFNQYVRDQGAMTDQLSRRQ


    Database link: O60258

  • Positive control

    • Human testis tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab187982 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
  • Tissue specificity

    Preferentially expressed in the embryonic brain.
  • Sequence similarities

    Belongs to the heparin-binding growth factors family.
  • Developmental stage

    Detected in embryos at E14.5, but not at E10.5 and E19.5. Preferentially expressed in the neuroepithelia of the isthmus and septum of the embryonic brain at E14.5.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • FGF 13 antibody
    • FGF 17 antibody
    • FGF-17 antibody
    • FGF13 antibody
    • Fgf17 antibody
    • FGF17_HUMAN antibody
    • Fibroblast growth factor 17 antibody
    • HH20 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human testis tissue labeling FGF17 with ab187982 at 1/50 dilution.

References

This product has been referenced in:

  • Clegg JM  et al. Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism. J Neurosci 39:1386-1404 (2019). Read more (PubMed: 30617207) »
See 1 Publication for this product

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