Anti-FGF19 antibody (ab172545)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-FGF19 antibody
See all FGF19 primary antibodies -
DescriptionMouse polyclonal to FGF19
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
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Immunogen
Full length protein corresponding to Human FGF19 aa 1-216.
Sequence:MRSGCVVVHVWILAGLWLAVAGRPLAFSDAGPHVHYGWGDPIRLRHLYTS GPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRY LCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQ RQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPF GLVTGLEAVRSPSFEK
Database link: NP_005108.1 -
Positive control
- FGF19 transfected 293T cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.2
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab172545 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. |
Target
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FunctionInvolved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
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Tissue specificityExpressed in fetal brain, cartilage, retina, and adult gall bladder.
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Sequence similaritiesBelongs to the heparin-binding growth factors family.
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Cellular localizationSecreted.
- Information by UniProt
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Database links
- Entrez Gene: 9965 Human
- Omim: 603891 Human
- SwissProt: O95750 Human
- Unigene: 249200 Human
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Alternative names
- FGF 19 antibody
- FGF-19 antibody
- FGF15 antibody
see all
Images
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Western blot - Anti-FGF19 antibody (ab172545)All lanes : Anti-FGF19 antibody (ab172545) at 1 µg/ml
Lane 1 : FGF19 transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
Predicted band size: 24 kDa
Protocols
Datasheets and documents
References
ab172545 has not yet been referenced specifically in any publications.
