Key features and details
- Rabbit polyclonal to FGFBP1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-FGFBP1 antibody
See all FGFBP1 primary antibodies
DescriptionRabbit polyclonal to FGFBP1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide within Human FGFBP1. The exact sequence is proprietary.
Database link: Q14512
- WB - A549 cell line lysate
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab215353 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/350 - 1/2000. Predicted molecular weight: 26 kDa.|
FunctionActs as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Tissue specificityExpressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas.
Sequence similaritiesBelongs to the fibroblast growth factor-binding protein family.
Cellular localizationSecreted, extracellular space. Cell membrane. Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.
- Information by UniProt
- 17 kDa HBGF-binding protein antibody
- 17 kDa heparin binding growth factor binding protein antibody
- 17 kDa heparin-binding growth factor-binding protein antibody
ab215353 has been referenced in 1 publication.
- Takei Y et al. FGFRL1 deficiency reduces motility and tumorigenic potential of cells derived from oesophageal squamous cell carcinomas. Oncol Lett 16:809-814 (2018). PubMed: 29963148