Key features and details
- Mouse polyclonal to FGFBP1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab67931 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).|
FunctionActs as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Tissue specificityExpressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas.
Sequence similaritiesBelongs to the fibroblast growth factor-binding protein family.
Cellular localizationSecreted, extracellular space. Cell membrane. Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.
- Information by UniProt
- 17 kDa HBGF-binding protein antibody
- 17 kDa heparin binding growth factor binding protein antibody
- 17 kDa heparin-binding growth factor-binding protein antibody
All lanes : Anti-FGFBP1 antibody (ab67931) at 1/500 dilution
Lane 1 : FGFBP1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
ab67931 has been referenced in 1 publication.
- Kim Y et al. Comparative proteomic profiling of pancreatic ductal adenocarcinoma cell lines. Mol Cells 37:888-98 (2014). PubMed: 25518923