Recombinant
RabMAb

Recombinant Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)

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Overview

  • Product name

    Anti-FGFR1 Oncogene Partner antibody [EPR9929]
    See all FGFR1 Oncogene Partner primary antibodies

  • Description

    Rabbit monoclonal [EPR9929] to FGFR1 Oncogene Partner

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, IP, Flow Cyt, ICC/IFmore details
    Unsuitable for: IHC-P

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide corresponding to residues in Human FGFR1 Oncogene Partner (UniProt O95684).

  • Positive control

    • HeLa, 293T and Saos-2 cell lysates; HeLa cells.

  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab156013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for IHC-P.

    • Target

    • Function

      Required for anchoring microtubules to the centrosomes.

    • Tissue specificity

      Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.

    • Involvement in disease

      Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity.

    • Sequence similarities

      Belongs to the FGFR1OP family.
      Contains 1 LisH domain.

    • Cellular localization

      Cytoplasm > cytoskeleton > centrosome. Associated with gamma-tubulin.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • FGFR1 oncogene partner antibody
      • FGFR1OP antibody
      • Fibroblast growth factor receptor 1 oncogene partner antibody
      • FOP antibody
      • FR1OP_HUMAN antibody
      • OTTHUMP00000017612 antibody
      • OTTHUMP00000017613 antibody
      see all

    Images

    • Western blot - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
      Western blot - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
      All lanes : Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Saos-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 43 kDa

    • Immunocytochemistry/ Immunofluorescence - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
      Immunocytochemistry/ Immunofluorescence - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
      Immunofluorescent analysis of HeLa cells labeling FGFR1 Oncogene Partner with ab156013 at 1/100 dilution.

    References

    ab156013 has not yet been referenced specifically in any publications.

    Publishing research using ab156013? Please let us know so that we can cite the reference in this datasheet.

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