Recombinant Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
![Western blot - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)](https://www.abcam.com/ps/products/156/ab156013/Images/ab156013-163358-anti-fgfr1-oncogene-partner-antibody-western-blot-hela-human.jpg "Western blot - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9929] to FGFR1 Oncogene Partner
- Suitable for: WB, ICC/IF
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-FGFR1 Oncogene Partner antibody [EPR9929]
See all FGFR1 Oncogene Partner primary antibodies -
Description
Rabbit monoclonal [EPR9929] to FGFR1 Oncogene Partner -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details
Unsuitable for: IHC-P -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat
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Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- HeLa, 293T and Saos-2 cell lysates; HeLa cells.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR9929 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab156013 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 43 kDa.
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| ICC/IF |
1/100 - 1/250.
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| Notes |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 43 kDa. |
|
ICC/IF
1/100 - 1/250. |
Application notes
Is unsuitable for IHC-P.
Target
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Function
Required for anchoring microtubules to the centrosomes. -
Tissue specificity
Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. -
Involvement in disease
Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity. -
Sequence similarities
Belongs to the FGFR1OP family.
Contains 1 LisH domain. -
Cellular localization
Cytoplasm > cytoskeleton > centrosome. Associated with gamma-tubulin. - Information by UniProt
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Database links
- Entrez Gene: 11116 Human
- Entrez Gene: 75296 Mouse
- Entrez Gene: 365103 Rat
- Entrez Gene: 683722 Rat
- Omim: 605392 Human
- SwissProt: O95684 Human
- SwissProt: Q66JX5 Mouse
- SwissProt: Q4V7C1 Rat
see all -
Alternative names
- FGFR1 oncogene partner antibody
- FGFR1OP antibody
- Fibroblast growth factor receptor 1 oncogene partner antibody
see all
Images
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Western blot - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)All lanes : Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013) at 1/1000 dilution
Lane 1 : HeLa cell lysate
Lane 2 : 293T cell lysate
Lane 3 : Saos-2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 43 kDa -
![Immunocytochemistry/ Immunofluorescence - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)](https://www.abcam.com/ps/products/156/ab156013/Images/ab156013-163357-anti-fgfr1-oncogene-partner-antibody-epr9929-immunofluorescence.jpg)
Immunocytochemistry/ Immunofluorescence - Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)Immunofluorescent analysis of HeLa cells labeling FGFR1 Oncogene Partner with ab156013 at 1/100 dilution. -
![Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)](https://www.abcam.com/ps/products/156/ab156013/Images/ab156013-3-benefits-of-recombinant-antibodies.png)
Anti-FGFR1 Oncogene Partner antibody [EPR9929] (ab156013)
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab156013 has been referenced in 1 publication.
- Jiang H et al. FOP Negatively Regulates Ciliogenesis and Promotes Cell Cycle Re-entry by Facilitating Primary Cilia Disassembly. Front Cell Dev Biol 8:590449 (2020). PubMed: 33304902
