Overview

  • Product name
  • Description
    Rabbit polyclonal to FGFR1OP2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human FGFR1OP2 aa 139-166 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9NVK5

  • Positive control
    • NIH 3T3 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab173884 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab173884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.

Target

  • Function
    May be involved in wound healing pathway.
  • Tissue specificity
    Expressed in bone marrow, spleen and thymus.
  • Involvement in disease
    Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
  • Sequence similarities
    Belongs to the SIKE family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp564O1863 antibody
    • FGFR1 oncogene partner 2 antibody
    • FGFR1OP2 antibody
    • FGOP2_HUMAN antibody
    • Fibroblast growth factor receptor 1 oncogene partner 2 antibody
    • HSPC123 antibody
    • HSPC123 like antibody
    • WIT3.0 antibody
    • Wound inducible transcript 3.0 antibody
    see all

Images

  • Anti-FGFR1OP2 antibody (ab173884) at 1/100 dilution + NIH 3T3 cell lysate at 35 µg

    Predicted band size: 29 kDa

References

ab173884 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab173884.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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