Overview

  • Product name

    Anti-FGFR1OP2 antibody
  • Description

    Rabbit polyclonal to FGFR1OP2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment within Human FGFR1OP2 (internal sequence). The exact sequence is proprietary.
    Database link: Q9NVK5

  • Positive control

    • WB: MCF7 whole cell lysate; mouse stomach tissue lysate. IHC-P: H441 xenograft tissue. ICC/IF: MCF7 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229119 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/1000.
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 29 kDa.

Target

  • Function

    May be involved in wound healing pathway.
  • Tissue specificity

    Expressed in bone marrow, spleen and thymus.
  • Involvement in disease

    Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
  • Sequence similarities

    Belongs to the SIKE family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp564O1863 antibody
    • FGFR1 oncogene partner 2 antibody
    • FGFR1OP2 antibody
    • FGOP2_HUMAN antibody
    • Fibroblast growth factor receptor 1 oncogene partner 2 antibody
    • HSPC123 antibody
    • HSPC123 like antibody
    • WIT3.0 antibody
    • Wound inducible transcript 3.0 antibody
    see all

Images

  • Anti-FGFR1OP2 antibody (ab229119) at 1/2000 dilution + MCF7 (human breast adenocarcinoma cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 29 kDa



    12% SDS-PAGE

  • Anti-FGFR1OP2 antibody (ab229119) at 1/1000 dilution + Mouse stomach tissue lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 29 kDa



    12% SDS-PAGE

  • Paraffin-embedded H441 xenograft tissue stained for FGFR1OP2 with ab229119 at 1/500 dilution in immunohistochemical analysis.

  • Methanol-fixed MCF7 (human breast adenocarcinoma cell line) cells stained for FGFR1OP2 (green) using ab229119 at 1/500 dilution in ICC/IF.

    Nuclear counterstain: Hoechst 33342 (blue).

References

ab229119 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229119.
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