Overview

  • Product name

    FH-535, Wnt/beta-cantenin inhibitor
  • Description

    Wnt/β-cantenin inhibitor and PPARγ and PPARδ antagonist
  • Biological description

    Wnt/β-cantenin inhibitor and PPARγ and PPARδ antagonist. Suppresses proliferation of cancer cells in vitro. Antitumor agent.
  • Purity

    > 98%
  • CAS Number

    108409-83-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Iida J  et al. FH535 inhibited migration and growth of breast cancer cells. PLoS One 7:e44418 (2012). Read more (PubMed: 22984505) »
  • Handeli S & Simon JA A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities. Mol Cancer Ther 7:521-9 (2008). Read more (PubMed: 18347139) »
  • Polk WW FH535 potentiation of cigarette smoke condensate cytotoxicity is associated with changes in ß-catenin and EGR-1 signaling. Int J Toxicol 31:380-9 (0). Read more (PubMed: 22713211) »

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