Overview

  • Product name

    Anti-FHOD1 antibody [5.3_1G6]
    See all FHOD1 primary antibodies
  • Description

    Mouse monoclonal [5.3_1G6] to FHOD1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Colorectal carcinoma (HCT116) cells

  • Positive control

    • HeLa cells in vitro and lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab128009 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 127 kDa.
ICC/IF 1/100.

Target

  • Function

    Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
  • Tissue specificity

    Ubiquitous. Highly expressed in spleen.
  • Sequence similarities

    Belongs to the formin homology family.
    Contains 1 FH1 (formin homology 1) domain.
    Contains 1 FH2 (formin homology 2) domain.
    Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
  • Domain

    Regulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein.
  • Cellular localization

    Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
  • Information by UniProt
  • Database links

  • Alternative names

    • FH1/FH2 domain containing protein antibody
    • FH1/FH2 domain containing protein 1 antibody
    • FH1/FH2 domain-containing protein 1 antibody
    • Fhod1 antibody
    • FHOD1_HUMAN antibody
    • FHOS antibody
    • FHOS1 antibody
    • Formin homolog overexpressed in spleen 1 antibody
    • Formin homology 2 domain containing 1 antibody
    • Formin homology 2 domain containing protein 1 antibody
    • Formin homology 2 domain-containing protein 1 antibody
    see all

Images

  • ab128009 at 1/100 staining FHOD1 in HeLa cells by Immunocytochemistry
  • Lanes 1-3 : Anti-FHOD1 antibody [5.3_1G6] (ab128009) at 1/1000 dilution
    Lanes 4-6 : V5 antibody control at 1/1000 dilution

    Lanes 1 & 5 : Transfected HeLa cell lysate
    Lanes 2 & 4 : Non-Transfected HeLa cell lysate
    Lanes 3 & 6 : SH-SY5Y cell lysate

    Predicted band size: 127 kDa

References

ab128009 has not yet been referenced specifically in any publications.

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