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Rabbit polyclonal to FHOD1 (phospho T1141)
The immunogen sequence is highly conserved in rat and mouse FHOD1, and is well conserved in FHOD3 (Thr-1399).
Predicted to work with:
Synthetic phosphopeptide conjugated to KLH, corresponding to amino acid residues surrounding Thr 1141 of Human FHOD1.
K562 cells and C2C12 cells stimulated with calyculin A.
Shipped at 4°C. Store at -20ºC.
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.1% BSA
Concentration information loading...
Immunogen affinity purified
ab157589 was cross-adsorbed to unphosphorylated FHOD1 (Thr-1141)
peptide before affinity purification using phospho-FHOD1 (Thr-1141) peptide (without carrier).
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 140 kDa (predicted molecular weight: 127 kDa).
Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Ubiquitous. Highly expressed in spleen.
Belongs to the formin homology family.
Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
Regulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein.
Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
Information by UniProt
FH1/FH2 domain containing protein antibody
FH1/FH2 domain containing protein 1 antibody
FH1/FH2 domain-containing protein 1 antibody
has not yet been referenced specifically in any publications.
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