Key features and details
- Rabbit polyclonal to FHOD1 (phospho T1141)
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-FHOD1 (phospho T1141) antibody
See all FHOD1 primary antibodies
DescriptionRabbit polyclonal to FHOD1 (phospho T1141)
SpecificityThe immunogen sequence is highly conserved in rat and mouse FHOD1, and is well conserved in FHOD3 (Thr-1399).
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Synthetic phosphopeptide conjugated to KLH, corresponding to amino acid residues surrounding Thr 1141 of Human FHOD1.
- K562 cells and C2C12 cells stimulated with calyculin A.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 0.1% BSA, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab157589 was cross-adsorbed to unphosphorylated FHOD1 (Thr-1141) peptide before affinity purification using phospho-FHOD1 (Thr-1141) peptide (without carrier).
Our Abpromise guarantee covers the use of ab157589 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 140 kDa (predicted molecular weight: 127 kDa).|
FunctionRequired for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Tissue specificityUbiquitous. Highly expressed in spleen.
Sequence similaritiesBelongs to the formin homology family.
Contains 1 FH1 (formin homology 1) domain.
Contains 1 FH2 (formin homology 2) domain.
Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
DomainRegulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein.
Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
- Information by UniProt
- FH1/FH2 domain containing protein antibody
- FH1/FH2 domain containing protein 1 antibody
- FH1/FH2 domain-containing protein 1 antibody
ab157589 has not yet been referenced specifically in any publications.