Anti-FILIP1L antibody (ab151331)
Key features and details
- Rabbit polyclonal to FILIP1L
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-FILIP1L antibody
See all FILIP1L primary antibodies -
Description
Rabbit polyclonal to FILIP1L -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse
-
Immunogen
Recombinant fragment, corresponding to a region within amino acids 252-487 of Human FILIP1L.
-
Positive control
- HCT116 and MCF7 whole cell lysates.
-
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab151331 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 130 kDa. |
Target
-
Function
Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature. -
Tissue specificity
Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer. -
Sequence similarities
Belongs to the FILIP1 family. -
Cellular localization
Cytoplasm. Membrane. Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 11259 Human
- Entrez Gene: 78749 Mouse
- Omim: 612993 Human
- SwissProt: Q4L180 Human
- SwissProt: Q6P6L0 Mouse
- Unigene: 104672 Human
- Unigene: 328360 Mouse
-
Alternative names
- 130 kDa GPBP-interacting protein antibody
- 90 kDa GPBP-interacting protein antibody
- COL4A3BPIP antibody
see all
Images
-
Western blot - Anti-FILIP1L antibody (ab151331)All lanes : Anti-FILIP1L antibody (ab151331) at 1/1000 dilution
Lane 1 : HCT116 whole cell lysate
Lane 2 : MCF7 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 130 kDa
7.5% SDS PAGE
References (0)
ab151331 has not yet been referenced specifically in any publications.
