Overview

  • Product name

  • Description

    Rabbit polyclonal to FIST
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Synthetic peptide corresponding to Human FIST aa 1152-1215 (C terminal).
    Database link: Q9H422

  • Positive control

    • A431, H1299, HeLa, HepG2 cell lines.
  • General notes

    Previously labelled as HIPK3.

Properties

Applications

Our Abpromise guarantee covers the use of ab151294 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 134 kDa.

Target

  • Function

    Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.
  • Tissue specificity

    Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Autophosphorylated, but autophosphorylation is not required for catalytic activity.
    May be sumoylated.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Androgen receptor interacting nuclear protein kinase antibody
    • Androgen receptor-interacting nuclear protein kinase antibody
    • ANPK antibody
    • DYRK6 antibody
    • Fas interacting serine/threonine protein kinase antibody
    • Fas-interacting serine/threonine-protein kinase antibody
    • FIST antibody
    • FIST3 antibody
    • Hipk3 antibody
    • HIPK3_HUMAN antibody
    • homeodomain interacting protein kinase 3 antibody
    • Homeodomain-interacting protein kinase 3 antibody
    • Homolog of protein kinase YAK1 antibody
    • PKY antibody
    • RP24 297H17.5 antibody
    • YAK1 antibody
    see all

Images

  • Anti-FIST antibody (ab151294) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size: 134 kDa



    5% SDS PAGE

References

ab151294 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab151294.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up