Key features and details
- Rabbit polyclonal to FIST
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-FIST antibody
See all FIST primary antibodies
DescriptionRabbit polyclonal to FIST
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Synthetic peptide corresponding to Human FIST aa 1152-1215 (C terminal).
Database link: Q9H422
- A431, H1299, HeLa, HepG2 cell lines.
Previously labelled as HIPK3.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab151294 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 134 kDa.|
FunctionSeems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.
Tissue specificityOverexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung.
Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
Contains 1 protein kinase domain.
modificationsAutophosphorylated, but autophosphorylation is not required for catalytic activity.
May be sumoylated.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- Androgen receptor interacting nuclear protein kinase antibody
- Androgen receptor-interacting nuclear protein kinase antibody
- ANPK antibody
ab151294 has not yet been referenced specifically in any publications.