FITC Anti-Annexin V/ANXA5 antibody [VAA-33] (ab63556)
Key features and details
- FITC Mouse monoclonal [VAA-33] to Annexin V/ANXA5
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Overview
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Product name
FITC Anti-Annexin V/ANXA5 antibody [VAA-33]
See all Annexin V/ANXA5 primary antibodies -
Description
FITC Mouse monoclonal [VAA-33] to Annexin V/ANXA5 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant full length protein corresponding to Human Annexin V/ANXA5.
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General notes
This product was previously labelled as Annexin V
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.605% Tris, 0.58% Sodium chloride, 1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
VAA-33 -
Isotype
IgG2a -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Target
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Function
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. -
Involvement in disease
Pregnancy loss, recurrent, 3 -
Sequence similarities
Belongs to the annexin family.
Contains 4 annexin repeats. -
Domain
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
Post-translational
modificationsS-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex. - Information by UniProt
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Database links
- Entrez Gene: 308 Human
- Entrez Gene: 11747 Mouse
- Omim: 131230 Human
- SwissProt: P08758 Human
- SwissProt: P48036 Mouse
- Unigene: 480653 Human
- Unigene: 1620 Mouse
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Alternative names
- Anchorin CII antibody
- Annexin 5 antibody
- Annexin A5 antibody
see all
References (3)
ab63556 has been referenced in 3 publications.
- Kang C et al. The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells. Int J Stem Cells 11:131-140 (2018). PubMed: 29699387
- Qin A et al. MicroRNA-1271 inhibits cellular proliferation of hepatocellular carcinoma. Oncol Lett 14:6783-6788 (2017). Flow Cyt . PubMed: 29181102
- Sacconi A et al. miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer. Cell Death Dis 3:e423 (2012). Flow Cyt . PubMed: 23152059