FITC Anti-CD103 antibody [2E7] (ab24938)
![Flow Cytometry - FITC Anti-CD103 antibody [2E7] (ab24938)](https://www.abcam.com/ps/products/24/ab24938/Images/ab24938-1-anti-cd103-antibody-2e7-fitc-flow-cytometry-mesenteric-lymph-node-cells-mouse.jpg "Flow Cytometry - FITC Anti-CD103 antibody [2E7] (ab24938)")
Key features and details
- FITC Armenian hamster monoclonal [2E7] to CD103
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Related conjugates and formulations
Overview
-
Product name
FITC Anti-CD103 antibody [2E7]
See all CD103 primary antibodies -
Description
FITC Armenian hamster monoclonal [2E7] to CD103 -
Host species
Armenian hamster -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
ab24938 recognises the CD103 complex (115 and 160 kDa subunits).
-
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to Mouse CD103. C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL)
-
Positive control
- Flow Cyt: Mouse mesenteric lymph node cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
2E7 -
Isotype
IgG -
Research areas
Associated products
-
Alternative Versions
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab24938 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
|
| Notes |
|---|
|
Flow Cyt
Use at an assay dependent concentration. |
Target
-
Function
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. -
Tissue specificity
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. -
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 16407 Mouse
- SwissProt: Q60677 Mouse
- Unigene: 96 Mouse
-
Alternative names
- A530055J10 antibody
- alpha-E1 antibody
- alpha-M290 antibody
see all
Images
-
Flow Cytometry - FITC Anti-CD103 antibody [2E7] (ab24938)
Mouse mesenteric lymph node cells were costained using CD103-FITC and CD3ε-PE to distinguish cell subpopulations. Cells were incubated with anti-CD103 antibody [2E7] (FITC) (ab24938) at 1 µg/106 cells.
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab24938 has been referenced in 1 publication.
- Kohan M et al. EDA-containing cellular fibronectin induces fibroblast differentiation through binding to {alpha}4{beta}7 integrin receptor and MAPK/Erk 1/2-dependent signaling. FASEB J : (2010). PubMed: 20643910