Key features and details
- FITC Rat monoclonal [MJ718] to CD105
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Product nameFITC Anti-CD105 antibody [MJ718]
See all CD105 primary antibodies
DescriptionFITC Rat monoclonal [MJ718] to CD105
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
Tissue, cells or virus corresponding to Mouse CD105. ab184667 was produced by immunizing rats with inflamed mouse skin (murine stromal cell line). NCBI Accession No. NP_031958.2
Database link: Q63961
- Mouse endothelial cells.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferPreservative: 0.02% Sodium azide
Constituents: 1% BSA, 98% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab184667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use a concentration of 5 µg/ml.
in a volume of 100 µl
ab18446 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
- Information by UniProt
- AI528660 antibody
- AI662476 antibody
- CD 105 antibody
Flow cytometry analysis of mouse endothelial cells labeling CD105. Upper panel: no primary antibody; Middle panel: solely conjugated secondary antibody; Lower panel: ab184667 at 5 µg/ml.
Flow cytometry analysis of mouse endothelial cells labeling CD105, using ab184667 at 5 µg/ml (red-filled histogram).
ab184667 has been referenced in 3 publications.
- Zhao SJ et al. Macrophage MSR1 promotes BMSC osteogenic differentiation and M2-like polarization by activating PI3K/AKT/GSK3ß/ß-catenin pathway. Theranostics 10:17-35 (2020). PubMed: 31903103
- Shojafar E et al. Adipose-derived mesenchymal stromal cell transplantation at the graft site improves the structure and function of autografted mice ovaries: a stereological and biochemical analysis. Cytotherapy 20:1324-1336 (2018). PubMed: 30360962
- Wang B et al. MicroRNA expression in bone marrow mesenchymal stem cells from mice with steroid-induced osteonecrosis of the femoral head. Mol Med Rep 12:7447-54 (2015). PubMed: 26459755