FITC Anti-CD11+CD18 antibody [24] (ab187835)

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Key features and details

  • FITC Mouse monoclonal [24] to CD11+CD18
  • Reacts with: Human
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG1

Conjugates logo Related conjugates and formulations

Unconjugated

Overview

  • Product name

    FITC Anti-CD11+CD18 antibody [24]
    See all CD11+CD18 primary antibodies

  • Description

    FITC Mouse monoclonal [24] to CD11+CD18

  • Host species

    Mouse

  • Conjugation

    FITC. Ex: 493nm, Em: 528nm

  • Specificity

    ab187835 recognises integrin alpha L,M,X/Beta 2 (CD11/CD18).

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Tissue, cells or virus corresponding to Human CD11+CD18. (Fibronectin-purified Human monocytes).

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Target

  • Function

    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.

  • Tissue specificity

    Leukocytes.

  • Sequence similarities

    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.

  • Domain

    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
    • CD11 antigen-like family member A antibody
    • CD11a antibody
    • CD18 antibody
    • CR3 antibody
    • Integrin alpha-L antibody
    • Integrin beta 2 antibody
    • Integrin gene promoter antibody
    • ITAL_HUMAN antibody
    • Itgal antibody
    • ITGAM antibody
    • ITGB2 antibody
    • LAD antibody
    • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
    • Leukocyte function-associated molecule 1 alpha chain antibody
    • LFA 1 alpha antibody
    • LFA 1 antibody
    • LFA-1A antibody
    • LFA1 antibody
    • LFA1A antibody
    • Lymphocyte function associated antigen 1 antibody
    • MAC1 antibody
    • MFI7 antibody
    • MO1A antibody
    see all

References (0)

Publishing research using ab187835? Please let us know so that we can cite the reference in this datasheet.

ab187835 has not yet been referenced specifically in any publications.

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