Key features and details
- FITC Mouse monoclonal [LT2] to CD2
- Suitable for: Flow Cyt
- Reacts with: Human, Rhesus monkey
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Product nameFITC Anti-CD2 antibody [LT2]
See all CD2 primary antibodies
DescriptionFITC Mouse monoclonal [LT2] to CD2
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab27995 recognises CD2 expressed by T cells, NK cells and thymocytes.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human, Rhesus monkey
Tissue/ cell preparation: Normal human peripheral blood lymphocytes.
ab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityProtein A purified
Primary antibody notesab27995 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.
Our Abpromise guarantee covers the use of ab27995 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 10µl for 106 cells.
Use 10µl for 106 cells, or 100µl of whole blood.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
FunctionCD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
- Information by UniProt
- CD 2 antibody
- CD2 antibody
- CD2 antigen (p50), sheep red blood cell receptor antibody
ab27995 has been referenced in 2 publications.
- Lin CW et al. CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood 106:3567-74 (2005). PubMed: 16046525
- Beyers AD et al. Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen. Immunol Rev 111:59-77 (1989). PubMed: 2576418