FITC Anti-CD21 antibody [LT21] (ab65809)

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Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)

    Key features and details

    • FITC Mouse monoclonal [LT21] to CD21
    • Suitable for: Flow Cyt
    • Reacts with: Cow, Human, Pig
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG1

    Overview

    • Product name

      FITC Anti-CD21 antibody [LT21]
      See all CD21 primary antibodies

    • Description

      FITC Mouse monoclonal [LT21] to CD21

    • Host species

      Mouse

    • Conjugation

      FITC. Ex: 493nm, Em: 528nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Cow, Human, Pig

    • Immunogen

      Tissue, cells or virus corresponding to Human CD21. IM9 human B-lymphoblastoid cell line

    • Positive control

      • Human blood

    • General notes


      CD21 is expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

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    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C.

    • Storage buffer

      pH: 7.4
      Preservative: 0.097% Sodium azide
      Constituents: PBS, 0.2% BSA
    • Concentration information loading...

    • Purity

      Size exclusion

    • Purification notes

      >95% pure (by SDS Page).

    • Primary antibody notes

      CD21 is expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.

    • Clonality

      Monoclonal

    • Clone number

      LT21

    • Isotype

      IgG1

    • Research areas

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab65809 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt
    Use at an assay dependent concentration.

    Use  20 μl per 100 μl of whole blood or 106 cells in a suspension.
    Notes
    Flow Cyt
    Use at an assay dependent concentration.

    Use  20 μl per 100 μl of whole blood or 106 cells in a suspension.

    Target

    • Function

      Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.

    • Tissue specificity

      Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.

    • Involvement in disease

      Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.

    • Sequence similarities

      Belongs to the receptors of complement activation (RCA) family.
      Contains 15 Sushi (CCP/SCR) domains.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • C3DR antibody
        • CD 21 antibody
        • CD21 antibody
        • Complement C3d receptor 2 antibody
        • Complement C3d receptor antibody
        • Complement component (3d/Epstein Barr virus) receptor 2 antibody
        • Complement receptor type 2 antibody
        • CR antibody
        • Cr2 antibody
        • CR2_HUMAN antibody
        • CVID7 antibody
        • EBV receptor antibody
        • EBV-R antibody
        • Epstein Barr virus receptor antibody
        • Epstein-Barr virus receptor antibody
        • EVBR antibody
        • SLEB9 antibody
        see all

      Images

      • Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)
        Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)

        Flow cytometry analysis (surface staining) of human peripheral blood leukocytes with ab65809

      References (0)

      Publishing research using ab65809? Please let us know so that we can cite the reference in this datasheet.

      ab65809 has not yet been referenced specifically in any publications.

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