Key features and details
- FITC Mouse monoclonal [DX11] to CD226
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Product nameFITC Anti-CD226 antibody [DX11]
See all CD226 primary antibodies
DescriptionFITC Mouse monoclonal [DX11] to CD226
ConjugationFITC. Ex: 493nm, Em: 528nm
SpecificityThis antibody recognises CD226.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Tissue/ cell preparation: Human cytotoxic T lymphocyte clone.
- Human peripheral blood lymphocytes.
Clone DX11 is reported to inhibit T and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen specific T cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityProtein G purified
Purification notesThis antibody was purified from tissue culture supernatant.
Primary antibody notesClone DX11 is reported to inhibit T and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen specific T cells.
Our Abpromise guarantee covers the use of ab33335 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||1/10 - 1/20.
Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionReceptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell.
Tissue specificityExpressed by peripheral blood T-lymphocytes.
Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains.
- Information by UniProt
- adhesion glycoprotein antibody
- CD226 antibody
- CD226 antigen antibody
ab33335 has been referenced in 1 publication.
- Kojima H et al. CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. J Biol Chem 278:36748-53 (2003). PubMed: 12847109