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Immunology Cell Type Markers CD Platelets
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FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

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Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

    Key features and details

    • FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG1

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    Anti-CD42a/GP-IX antibody [EPR5295] - BSA and Azide free (ab247625)

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    Overview

    • Product name

      FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted
      See all CD42a/GP-IX primary antibodies
    • Description

      FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted
    • Host species

      Mouse
    • Conjugation

      FITC. Ex: 493nm, Em: 528nm
    • Tested Applications & Species

      Application Species
      Flow Cyt
      Human
      See all applications and species data
    • Immunogen

      Tissue, cells or virus corresponding to Human CD42a/GP-IX. (Human acute lymphoblastic leukemia cells).

    • General notes

      Previously labelled as CD42a. 

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C. Store In the Dark.
    • Storage buffer

      pH: 7.4
      Preservative: 0.097% Sodium azide
      Constituents: 99% PBS, 0.2% BSA
    • Concentration information loading...
    • Purity

      Size exclusion
    • Purification notes

      Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
    • Clonality

      Monoclonal
    • Clone number

      GR-P
    • Isotype

      IgG1
    • Research areas

      • Immunology
      • Cell Type Markers
      • CD
      • Platelets

    Associated products

    • Alternative Versions

      • CF405M Anti-CD42a/GP-IX antibody [GR-P] (ab119483)
      • PE Anti-CD42a/GP-IX antibody [GR-P] (ab30399)
    • Isotype control

      • FITC Mouse IgG1 [B11/6] - Isotype Control (ab91356)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab194810 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    Flow Cyt
    Human
    Application Abreviews Notes
    Flow Cyt
    Use 4µl for 106 cells.

    (or 100 μl of whole blood).

     

     

     

     

    ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

     

    Notes
    Flow Cyt
    Use 4µl for 106 cells.

    (or 100 μl of whole blood).

     

     

     

     

    ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
    • Involvement in disease

      Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
    • Sequence similarities

      Contains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession P14770 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 2815 Human
      • Omim: 173515 Human
      • SwissProt: P14770 Human
      • Unigene: 1144 Human
      • Alternative names

        • CD42a antibody
        • Glycoprotein 9 antibody
        • Glycoprotein IX antibody
        • Glycoprotein IX (platelet) antibody
        • Glycoprotein IX precursor antibody
        • GP IX antibody
        • GP-IX antibody
        • GP9 antibody
        • GPIX antibody
        • GPIX_HUMAN antibody
        • Platelet glycoprotein IX antibody
        see all

      Images

      • Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)
        Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

        Surface staining of human platelets with ab194810.

      Protocols

      • Flow cytometry protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (0)

      Publishing research using ab194810? Please let us know so that we can cite the reference in this datasheet.

      ab194810 has not yet been referenced specifically in any publications.

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