FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

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Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

    Key features and details

    • FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted
    • Suitable for: Flow Cyt
    • Reacts with: Dog, Human
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG1

    Overview

    • Product name

      FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted
      See all CD42a/GP-IX primary antibodies

    • Description

      FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted

    • Host species

      Mouse

    • Conjugation

      FITC. Ex: 493nm, Em: 528nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Dog, Human

    • Immunogen

      Tissue, cells or virus corresponding to Human CD42a/GP-IX. (Human acute lymphoblastic leukemia cells).

    • General notes

      Previously labelled as CD42a. 

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C. Store In the Dark.

    • Storage buffer

      pH: 7.4
      Preservative: 0.097% Sodium azide
      Constituents: 99% PBS, 0.2% BSA
    • Concentration information loading...

    • Purity

      Size exclusion

    • Purification notes

      Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    • Clonality

      Monoclonal

    • Clone number

      GR-P

    • Isotype

      IgG1

    • Research areas

    Applications

    Our Abpromise guarantee covers the use of ab194810 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 4µl for 106 cells.

    (or 100 μl of whole blood).

     

     

     

     

    ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

     

    Target

    • Function

      The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.

    • Involvement in disease

      Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.

    • Sequence similarities

      Contains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CD42a antibody
        • Glycoprotein 9 antibody
        • Glycoprotein IX antibody
        • Glycoprotein IX (platelet) antibody
        • Glycoprotein IX precursor antibody
        • GP IX antibody
        • GP-IX antibody
        • GP9 antibody
        • GPIX antibody
        • GPIX_HUMAN antibody
        • Platelet glycoprotein IX antibody
        see all

      Images

      • Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)
        Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)

        Surface staining of human platelets with ab194810.

      References (0)

      Publishing research using ab194810? Please let us know so that we can cite the reference in this datasheet.

      ab194810 has not yet been referenced specifically in any publications.

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