FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)
Key features and details
- FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted
- Suitable for: Flow Cyt
- Reacts with: Dog, Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted
See all CD42a/GP-IX primary antibodies -
Description
FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Dog, Human -
Immunogen
Tissue, cells or virus corresponding to Human CD42a/GP-IX. (Human acute lymphoblastic leukemia cells).
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General notes
Previously labelled as CD42a.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading...
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Purity
Size exclusion -
Purification notes
Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary. -
Clonality
Monoclonal -
Clone number
GR-P -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab194810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt | Use 4µl for 106 cells. (or 100 μl of whole blood).
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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Target
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Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
Involvement in disease
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
Sequence similarities
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 609630 Dog
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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Alternative names
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
Images
Datasheets and documents
References (0)
ab194810 has not yet been referenced specifically in any publications.