FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)
![Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)](https://www.abcam.com/ps/products/194/ab194810/Images/ab194810-319740-anti-cd42a-gp-ix-antibody-gr-p-prediluted-fitc-flow-cytometry.jpg "Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)")
Key features and details
- FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted
See all CD42a/GP-IX primary antibodies -
Description
FITC Mouse monoclonal [GR-P] to CD42a/GP-IX, prediluted -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Human
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Immunogen
Tissue, cells or virus corresponding to Human CD42a/GP-IX. (Human acute lymphoblastic leukemia cells).
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General notes
Previously labelled as CD42a.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary. -
Clonality
Monoclonal -
Clone number
GR-P -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab194810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| Flow Cyt |
Human
|
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 4µl for 106 cells.
(or 100 μl of whole blood).
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
| Notes |
|---|
|
Flow Cyt
Use 4µl for 106 cells. (or 100 μl of whole blood).
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
Target
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Function
The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. -
Involvement in disease
Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency. -
Sequence similarities
Contains 1 LRR (leucine-rich) repeat.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 2815 Human
- Omim: 173515 Human
- SwissProt: P14770 Human
- Unigene: 1144 Human
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Alternative names
- CD42a antibody
- Glycoprotein 9 antibody
- Glycoprotein IX antibody
see all
Images
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Flow Cytometry - FITC Anti-CD42a/GP-IX antibody [GR-P], prediluted (ab194810)
Surface staining of human platelets with ab194810.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab194810 has not yet been referenced specifically in any publications.