FITC Anti-Cyclin B1 antibody [V152] (ab187806)

Submit a review Submit a question

Key features and details

  • FITC Mouse monoclonal [V152] to Cyclin B1
  • Reacts with: Human
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG1

Overview

  • Product name

    FITC Anti-Cyclin B1 antibody [V152]
    See all Cyclin B1 primary antibodies

  • Description

    FITC Mouse monoclonal [V152] to Cyclin B1

  • Host species

    Mouse

  • Conjugation

    FITC. Ex: 493nm, Em: 528nm

  • Specificity

    ab187806 recognises G2/mitotic-specific cyclin-B1. Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin B1 is a marker of cell proliferation and a key component of the cell cycle progression machinery. ab187806 recognises an epitope within the C-terminal region of cyclin B1.

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant full length protein (His-tag) corresponding to Hamster Cyclin B1. Expressed in bacteria, harvested from inclusion bodies
    Database link: P14635

  • Epitope

    ab187806 recognises an epitope within the C-terminal region of cyclin B1.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Target

  • Function

    Essential for the control of the cell cycle at the G2/M (mitosis) transition.

  • Sequence similarities

    Belongs to the cyclin family. Cyclin AB subfamily.

  • Developmental stage

    Accumulates steadily during G2 and is abruptly destroyed at mitosis.

  • Post-translational
    modifications

    Ubiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.

  • Cellular localization

    Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.
  • Information by UniProt

  • Database links

    • Alternative names

      • CCNB 1 antibody
      • CCNB antibody
      • ccnb1 antibody
      • CCNB1_HUMAN antibody
      • Cyclin B1 antibody
      • G2 mitotic specific cyclin B1 antibody
      • G2/mitotic-specific cyclin-B1 antibody
      see all

    References (0)

    Publishing research using ab187806? Please let us know so that we can cite the reference in this datasheet.

    ab187806 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab187806.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com