Key features and details
- FITC Goat polyclonal to Cytomegalovirus AD169
- Suitable for: ICC, IHC-P
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameFITC Anti-Cytomegalovirus AD169 antibody
See all Cytomegalovirus AD169 primary antibodies
DescriptionFITC Goat polyclonal to Cytomegalovirus AD169
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab30952 recognises Cytomegalovirus strain AD169.
Tested applicationsSuitable for: ICC, IHC-Pmore details
Species reactivityReacts with: Other species
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
Purification notesChromatographically purified IgG fraction.
Our Abpromise guarantee covers the use of ab30952 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC||Use at an assay dependent concentration.|
|IHC-P||Use at an assay dependent concentration.|
RelevanceCytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
- HCMV antibody
- HHV5 antibody
- Human Herpesvirus 5 antibody
- UL55 (strain AD169) antibody
ab30952 has not yet been referenced specifically in any publications.