FITC Anti-FOXP3 antibody [3G3] (ab210230)
![Flow Cytometry (Intracellular) - FITC Anti-FOXP3 antibody [3G3] (ab210230)](https://www.abcam.com/ps/products/210/ab210230/Images/ab210230-256653-anti-foxp3-antibody-3g3-fitc-flow-cytometry.jpg "Flow Cytometry (Intracellular) - FITC Anti-FOXP3 antibody [3G3] (ab210230)")
Key features and details
- FITC Mouse monoclonal [3G3] to FOXP3
- Suitable for: Flow Cyt (Intra)
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-FOXP3 antibody [3G3]
See all FOXP3 primary antibodies -
Description
FITC Mouse monoclonal [3G3] to FOXP3 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cyt (Intra)more details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rhesus monkey
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Flow Cyt (Intra): Mouse spleen cells (C57Bl/6 splenocytes)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.87% Sodium chloride, 0.05% BSA, 0.12% Tris -
Concentration information loading... -
Purity
Affinity purified -
Purification notes
ab210230 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation -
Clonality
Monoclonal -
Clone number
3G3 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab210230 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt (Intra) |
Use at an assay dependent concentration.
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| Notes |
|---|
|
Flow Cyt (Intra)
Use at an assay dependent concentration. |
Target
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Function
Probable transcription factor. Plays a critical role in the control of immune response. -
Involvement in disease
Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. -
Sequence similarities
Contains 1 C2H2-type zinc finger.
Contains 1 fork-head DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 20371 Mouse
- SwissProt: Q99JB6 Mouse
- Unigene: 182291 Mouse
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Alternative names
- AIID antibody
- DIETER antibody
- Forkhead box P3 antibody
see all
Images
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Flow Cytometry (Intracellular) - FITC Anti-FOXP3 antibody [3G3] (ab210230)
Intracellular flow cytometric analysis of Mouse C57Bl/6 splenocytes stained with APC Anti-Mouse CD4, followed by intracellular labeling of Foxp3 with ab210230 at 0.015 ug/test (right panel) or FITC Mouse IgG1 isotype control at 0.015 ug/test (left panel).
Datasheets and documents
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Datasheet download
References (0)
ab210230 has not yet been referenced specifically in any publications.
