FITC Anti-FOXP3 antibody [3G3] (ab210230)
![Flow Cytometry - FITC Anti-FOXP3 antibody [3G3] (ab210230)](https://www.abcam.com/ps/products/210/ab210230/Images/ab210230-256653-anti-foxp3-antibody-3g3-fitc-flow-cytometry.jpg "Flow Cytometry - FITC Anti-FOXP3 antibody [3G3] (ab210230)")
Key features and details
- FITC Mouse monoclonal [3G3] to FOXP3
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Overview
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Product name
FITC Anti-FOXP3 antibody [3G3]
See all FOXP3 primary antibodies -
Description
FITC Mouse monoclonal [3G3] to FOXP3 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rhesus monkey
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Mouse spleen cells (C57Bl/6 splenocytes)
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.87% Sodium chloride, 0.05% BSA, 0.12% Tris -
Concentration information loading... -
Purity
Affinity purified -
Purification notes
ab210230 was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation -
Clonality
Monoclonal -
Clone number
3G3 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab210230 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use at an assay dependent concentration. |
Target
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Function
Probable transcription factor. Plays a critical role in the control of immune response. -
Involvement in disease
Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. -
Sequence similarities
Contains 1 C2H2-type zinc finger.
Contains 1 fork-head DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 20371 Mouse
- SwissProt: Q99JB6 Mouse
- Unigene: 182291 Mouse
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Alternative names
- AIID antibody
- DIETER antibody
- Forkhead box P3 antibody
see all
Images
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Flow Cytometry - FITC Anti-FOXP3 antibody [3G3] (ab210230)
Flow cytometric analysis of Mouse C57Bl/6 splenocytes stained with APC Anti-Mouse CD4, followed by intracellular labeling of Foxp3 with ab210230 at 0.015 ug/test (right panel) or FITC Mouse IgG1 isotype control at 0.015 ug/test (left panel).
Datasheets and documents
References (0)
ab210230 has not yet been referenced specifically in any publications.
