FITC Anti-GITR antibody [DTA-1] (ab72404)
Key features and details
- FITC Rat monoclonal [DTA-1] to GITR
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
Overview
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Product name
FITC Anti-GITR antibody [DTA-1]
See all GITR primary antibodies -
Description
FITC Rat monoclonal [DTA-1] to GITR -
Host species
Rat -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to TNFSF18/GITRL. Mouse CD25+ CD4+ T cell line.
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Positive control
- Flow Cyt: Mouse splenocytes.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 8.00
Preservative: 0.05% Sodium azide
Constituents: 0.88% Sodium chloride, 0.12% Tris, 0.05% BSA -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
DTA-1 -
Isotype
IgG2b -
Light chain type
lambda -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72404 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
Target
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Function
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. -
Tissue specificity
Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. -
Sequence similarities
Contains 3 TNFR-Cys repeats. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 21936 Mouse
- SwissProt: O35714 Mouse
- Unigene: 482508 Mouse
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Alternative names
- Activation inducible TNFR family receptor antibody
- Activation-inducible TNFR family receptor antibody
- AITR antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab72404 has been referenced in 1 publication.
- Zhou Y et al. MicroRNA-30a controls the instability of inducible CD4+ Tregs through SOCS1. Mol Med Rep 20:4303-4314 (2019). PubMed: 31545427