Key features and details
- FITC Rabbit polyclonal to Hepatitis B Virus Surface Antigen
- Suitable for: ICC/IF
- Reacts with: Hepatitis B virus
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameFITC Anti-Hepatitis B Virus Surface Antigen antibody
See all Hepatitis B Virus Surface Antigen primary antibodies
DescriptionFITC Rabbit polyclonal to Hepatitis B Virus Surface Antigen
ConjugationFITC. Ex: 493nm, Em: 528nm
SpecificityMonospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. This product is non-reactive with normal human serum.
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Hepatitis B virus
Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.
Covalently coupled with high purity Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 0.0268% PBS, 1% BSA
Concentration information loading...
PurityProtein A purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab21021 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
Cellular localizationVirion membrane
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
ab21021 has been referenced in 1 publication.
- Li G et al. Recombinant covalently closed circular DNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model. Hepatology 67:56-70 (2018). PubMed: 28749559