FITC Anti-Hepatitis B Virus Surface Antigen antibody (ab21021)
Key features and details
- FITC Rabbit polyclonal to Hepatitis B Virus Surface Antigen
- Suitable for: ICC/IF
- Reacts with: Hepatitis B virus
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Overview
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Product name
FITC Anti-Hepatitis B Virus Surface Antigen antibody
See all Hepatitis B Virus Surface Antigen primary antibodies -
Description
FITC Rabbit polyclonal to Hepatitis B Virus Surface Antigen -
Host species
Rabbit -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. This product is non-reactive with normal human serum. -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Hepatitis B virus -
Immunogen
Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.
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General notes
Covalently coupled with high purity Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituents: 0.0268% PBS, 1% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab21021 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF |
| Notes |
|---|
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Relevance
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction. -
Cellular localization
Virion membrane -
Database links
- Entrez Gene: 2703546 Hepatitis B virus
- SwissProt: P03142 Hepatitis B virus
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Alternative names
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab21021 has been referenced in 1 publication.
- Li G et al. Recombinant covalently closed circular DNA of hepatitis B virus induces long-term viral persistence with chronic hepatitis in a mouse model. Hepatology 67:56-70 (2018). PubMed: 28749559