Key features and details
- FITC Rabbit polyclonal to HIV1 tat
- Suitable for: Flow Cyt
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameFITC Anti-HIV1 tat antibody
See all HIV1 tat primary antibodies
DescriptionFITC Rabbit polyclonal to HIV1 tat
ConjugationFITC. Ex: 493nm, Em: 528nm
SpecificityThis antibody is specific for Tat protein and GST-Tat fusion protein.
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Other species
Recombinant full length protein expressed in E. coli.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A purified
Matched antibody pairs
Our Abpromise guarantee covers the use of ab43016 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
For general use, dilute at 1:1 (V/V) in PBS.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceHIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Cellular localizationNuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
- p14 antibody
- Protein Tat antibody
- Transactivating regulatory protein antibody
ab43016 has been referenced in 2 publications.
- Li H et al. The glucocorticoid receptor-FKBP51 complex contributes to fear conditioning and posttraumatic stress disorder. J Clin Invest 130:877-889 (2020). PubMed: 31929189
- Hategan A et al. HIV Tat protein and amyloid-ß peptide form multifibrillar structures that cause neurotoxicity. Nat Struct Mol Biol 24:379-386 (2017). PubMed: 28218748