FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)
![Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)](https://www.abcam.com/ps/products/210/ab210240/Images/ab210240-256867-ab2102405.jpg "Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)")
Key features and details
- FITC Rat monoclonal [A7R34] to IL-17RA Receptor
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Overview
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Product name
FITC Anti-IL-17RA Receptor antibody [A7R34]
See all IL-17RA Receptor primary antibodies -
Description
FITC Rat monoclonal [A7R34] to IL-17RA Receptor -
Host species
Rat -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested Applications & Species
See all applications and species dataApplication Species Flow Cyt Rat
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- C57Bl/6 splenocytes.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin -
Concentration information loading... -
Purity
Protein A purified -
Purification notes
This antibody was purified from tissue culture supernatant via affinity chromatography. It was conjugated under optimal conditions, with unreacted dye removed from the preparation. -
Clonality
Monoclonal -
Clone number
A7R34 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab210240 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| Flow Cyt |
Rat
|
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
|
| Notes |
|---|
|
Flow Cyt
Use at an assay dependent concentration. |
Target
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Function
Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling. -
Tissue specificity
Widely expressed. -
Involvement in disease
Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. -
Sequence similarities
Contains 1 SEFIR domain. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 16172 Mouse
- SwissProt: Q60943 Mouse
- Unigene: 4481 Mouse
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Alternative names
- CANDF5 antibody
- CD217 antibody
- CD217 antigen antibody
see all
Images
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Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)
Flow cytometric analysis of C57Bl/6 splenocytes labeling IL17A with APC Anti-Mouse CD3 followed by ab210240 at 1 µg (right histogram) compared to a negative control cell which utilised 1 ug FITC Rat IgG2a isotype control (left histogram).
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab210240 has not yet been referenced specifically in any publications.