FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

Submit a review Submit a question
Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

    Key features and details

    • FITC Rat monoclonal [A7R34] to IL-17RA Receptor
    • Suitable for: Flow Cyt
    • Reacts with: Mouse
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG2a

    Overview

    • Product name

      FITC Anti-IL-17RA Receptor antibody [A7R34]
      See all IL-17RA Receptor primary antibodies

    • Description

      FITC Rat monoclonal [A7R34] to IL-17RA Receptor

    • Host species

      Rat

    • Conjugation

      FITC. Ex: 493nm, Em: 528nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Mouse

    • Immunogen

      The details of the immunogen for this antibody are not available.

    • Positive control

      • C57Bl/6 splenocytes.

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid

    • Storage instructions

      Shipped at 4°C. Store at +4°C. Store In the Dark.

    • Storage buffer

      pH: 7.20
      Preservative: 0.09% Sodium azide
      Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
    • Concentration information loading...

    • Purity

      Protein A purified

    • Purification notes

      This antibody was purified from tissue culture supernatant via affinity chromatography. It was conjugated under optimal conditions, with unreacted dye removed from the preparation.

    • Clonality

      Monoclonal

    • Clone number

      A7R34

    • Isotype

      IgG2a

    • Light chain type

      kappa

    • Research areas

    Applications

    Our Abpromise guarantee covers the use of ab210240 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use at an assay dependent concentration.

    Target

    • Function

      Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.

    • Tissue specificity

      Widely expressed.

    • Involvement in disease

      Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.

    • Sequence similarities

      Contains 1 SEFIR domain.

    • Post-translational
      modifications

      Glycosylated.

    • Cellular localization

      Membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • CANDF5 antibody
        • CD217 antibody
        • CD217 antigen antibody
        • CDw217 antibody
        • CTLA8 antibody
        • HIL 17R antibody
        • hIL17R antibody
        • I17RA_HUMAN antibody
        • IL 17 receptor A antibody
        • IL 17 receptor antibody
        • IL 17RA antibody
        • IL-17 receptor A antibody
        • IL-17RA antibody
        • IL17 antibody
        • IL17A receptor antibody
        • IL17R antibody
        • IL17RA antibody
        • IMD51 antibody
        • Interleukin 17 receptor A antibody
        • Interleukin-17 receptor A antibody
        • MGC10262 antibody
        see all

      Images

      • Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)
        Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

        Flow cytometric analysis of C57Bl/6 splenocytes labeling IL17A with APC Anti-Mouse CD3 followed by ab210240 at 1 µg (right histogram) compared to a negative control cell which utilised 1 ug FITC Rat IgG2a isotype control (left histogram).

      References (0)

      Publishing research using ab210240? Please let us know so that we can cite the reference in this datasheet.

      ab210240 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      There are currently no Customer reviews or Questions for ab210240.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com