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    fitc-il-17ra-receptor-antibody-a7r34-ab210240.pdf

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Immunology Innate Immunity Macrophage / Inflamm.
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FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

  • Datasheet
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Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

    Key features and details

    • FITC Rat monoclonal [A7R34] to IL-17RA Receptor
    • Suitable for: Flow Cyt
    • Reacts with: Mouse
    • Conjugation: FITC. Ex: 493nm, Em: 528nm
    • Isotype: IgG2a

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    Overview

    • Product name

      FITC Anti-IL-17RA Receptor antibody [A7R34]
      See all IL-17RA Receptor primary antibodies
    • Description

      FITC Rat monoclonal [A7R34] to IL-17RA Receptor
    • Host species

      Rat
    • Conjugation

      FITC. Ex: 493nm, Em: 528nm
    • Tested Applications & Species

      Application Species
      Flow Cyt
      Rat
      See all applications and species data
    • Immunogen

      The details of the immunogen for this antibody are not available.

    • Positive control

      • C57Bl/6 splenocytes.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C. Store In the Dark.
    • Storage buffer

      pH: 7.20
      Preservative: 0.09% Sodium azide
      Constituents: 0.12% Monobasic dihydrogen sodium phosphate, 0.87% Sodium chloride, 0.1% Gelatin
    • Concentration information loading...
    • Purity

      Protein A purified
    • Purification notes

      This antibody was purified from tissue culture supernatant via affinity chromatography. It was conjugated under optimal conditions, with unreacted dye removed from the preparation.
    • Clonality

      Monoclonal
    • Clone number

      A7R34
    • Isotype

      IgG2a
    • Light chain type

      kappa
    • Research areas

      • Immunology
      • Innate Immunity
      • Macrophage / Inflamm.
      • Immunology
      • Innate Immunity
      • Cytokines
      • Interleukins

    Associated products

    • Alternative Versions

      • APC Anti-CD127 antibody [A7R34] (ab210238)
    • Isotype control

      • FITC Rat IgG2a, kappa monoclonal [RTK2758] - Isotype control (ab18446)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab210240 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    Application Species
    Flow Cyt
    Rat
    Application Abreviews Notes
    Flow Cyt
    Use at an assay dependent concentration.
    Notes
    Flow Cyt
    Use at an assay dependent concentration.

    Target

    • Function

      Receptor for IL17A and IL17F. Binds its IL17A ligand with low affinity, suggesting that additional components are involved in IL17A-induced signaling.
    • Tissue specificity

      Widely expressed.
    • Involvement in disease

      Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) [MIM:613953]. CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
    • Sequence similarities

      Contains 1 SEFIR domain.
    • Post-translational
      modifications

      Glycosylated.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession Q96F46 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 16172 Mouse
      • SwissProt: Q60943 Mouse
      • Unigene: 4481 Mouse
      • Alternative names

        • CANDF5 antibody
        • CD217 antibody
        • CD217 antigen antibody
        • CDw217 antibody
        • CTLA8 antibody
        • HIL 17R antibody
        • hIL17R antibody
        • I17RA_HUMAN antibody
        • IL 17 receptor A antibody
        • IL 17 receptor antibody
        • IL 17RA antibody
        • IL-17 receptor A antibody
        • IL-17RA antibody
        • IL17 antibody
        • IL17A receptor antibody
        • IL17R antibody
        • IL17RA antibody
        • IMD51 antibody
        • Interleukin 17 receptor A antibody
        • Interleukin-17 receptor A antibody
        • MGC10262 antibody
        see all

      Images

      • Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)
        Flow Cytometry - FITC Anti-IL-17RA Receptor antibody [A7R34] (ab210240)

        Flow cytometric analysis of C57Bl/6 splenocytes labeling IL17A with APC Anti-Mouse CD3 followed by ab210240 at 1 µg (right histogram) compared to a negative control cell which utilised 1 ug FITC Rat IgG2a isotype control (left histogram).

      Protocols

      • Flow cytometry protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (0)

      Publishing research using ab210240? Please let us know so that we can cite the reference in this datasheet.

      ab210240 has not yet been referenced specifically in any publications.

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