FITC Anti-IL-4 antibody [CC303] (ab186716)
Key features and details
- FITC Mouse monoclonal [CC303] to IL-4
- Reacts with: Sheep, Goat, Horse, Cow, Dog, Pig, Mink, Dolphin
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Overview
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Product name
FITC Anti-IL-4 antibody [CC303]
See all IL-4 primary antibodies -
Description
FITC Mouse monoclonal [CC303] to IL-4 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Species reactivity
Reacts with: Sheep, Goat, Horse, Cow, Dog, Pig, Mink, Dolphin -
Immunogen
The details of the immunogen for this antibody are not available.
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General notes
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
ab186716 was prepared by affinity chromatography on Protein G from tissue culture supernatant. -
Clonality
Monoclonal -
Clone number
CC303 -
Isotype
IgG2a -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Target
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Function
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. -
Involvement in disease
Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. -
Sequence similarities
Belongs to the IL-4/IL-13 family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 280824 Cow
- Entrez Gene: 403785 Dog
- Entrez Gene: 101338293 Dolphin
- Entrez Gene: 100860814 Goat
- Entrez Gene: 100034225 Horse
- Entrez Gene: 397225 Pig
- SwissProt: P30367 Cow
- SwissProt: O77762 Dog
see all -
Alternative names
- B cell growth factor 1 antibody
- B cell IgG differentiation factor antibody
- B Cell Stimulatory Factor 1 antibody
see all
Datasheets and documents
References (0)
ab186716 has not yet been referenced specifically in any publications.
