FITC Anti-Malondialdehyde antibody (ab27615)
Key features and details
- FITC Goat polyclonal to Malondialdehyde
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Overview
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Product name
FITC Anti-Malondialdehyde antibody
See all Malondialdehyde primary antibodies -
Description
FITC Goat polyclonal to Malondialdehyde -
Host species
Goat -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
This antibody specifically binds to Malondialdehyde. -
Immunogen
Chemical/ Small Molecule MDA modified protein
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General notes
Molar FITC/ Protein ratio is 3.1
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0146% EDTA, 0.435% Sodium chloride, 0.5% BSA, 30% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
Purified by Malondialdehyde modified protein-Sepharose™ affinity column. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Target
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Relevance
Malondialdehyde (MDA) is a natural product formed in all mammalian cells as a product of lipid peroxidation. MDA is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. It reacts with DNA to form adducts to deoxyguanosine and deoxyadenosine. The major adduct to DNA is a pyrimidopurinone called M1G which appears to be a major endogenous DNA adduct in human beings that may contribute significantly to cancer linked to lifestyle and dietary factors. MDA modified proteins may show altered physico chemical behavior and antigenicity. MDA is toxic and has been implicated in aging mutagenesis, carcinogenesis, diabetic nephropathy and radiation damage. Increased expression of MDA has been reported in the brains of Alzheimer's patients. Antibodies to MDA will help to visualize the MDA adducts. -
Alternative names
- 1133 Tetramethoxypropane antibody
- MDA antibody
Protocols
Datasheets and documents
References (0)
ab27615 has not yet been referenced specifically in any publications.
