FITC Anti-MD2 antibody [18H10] (ab106105)
Key features and details
- FITC Mouse monoclonal [18H10] to MD2
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Overview
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Product name
FITC Anti-MD2 antibody [18H10]
See all MD2 primary antibodies -
Description
FITC Mouse monoclonal [18H10] to MD2 -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
ab106105 reacts with MD2. However, it does not react with sMD2. -
Species reactivity
Reacts with: Human -
Immunogen
TLR4/MD2 expressing CHO cells/ chimeric TLR4/MD2 fusion protein
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General notes
The monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Constituents: 1% BSA, PBS -
Concentration information loading...
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Purity
Protein G purified -
Primary antibody notes
The monoclonal antibody 18H10 is able to inhibit bacterial binding to MD2. -
Clonality
Monoclonal -
Clone number
18H10 -
Isotype
IgG2b -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Target
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Function
Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS. -
Post-translational
modificationsN-glycosylated; high-mannose. -
Cellular localization
Secreted > extracellular space. - Information by UniProt
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Database links
- Entrez Gene: 23643 Human
- Omim: 605243 Human
- SwissProt: Q9Y6Y9 Human
- Unigene: 726603 Human
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Alternative names
- ESOP 1 antibody
- ESOP-1 antibody
- ESOP1 antibody
see all
Datasheets and documents
References (0)
ab106105 has not yet been referenced specifically in any publications.