Key features and details
- FITC Goat polyclonal to Nitro tyrosine
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameFITC Anti-Nitro tyrosine antibody
See all Nitro tyrosine primary antibodies
DescriptionFITC Goat polyclonal to Nitro tyrosine
ConjugationFITC. Ex: 493nm, Em: 528nm
SpecificitySpecifically binds to nitrated proteins. Molar F/P ratio is 4.6.
Chemical/ Small Molecule (Nitrtyrosine modified protein)
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0146% EDTA, 0.435% Sodium chloride
Concentration information loading...
Purification notesPurified by nitrated protein-Sepharose™ affinity column.
RelevanceNitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
- NO tyrosine antibody
- nTyr antibody
ab27647 has not yet been referenced specifically in any publications.