FITC Anti-NKR-P1C antibody [PK136] (ab25026)
Key features and details
- FITC Mouse monoclonal [PK136] to NKR-P1C
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Overview
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Product name
FITC Anti-NKR-P1C antibody [PK136]
See all NKR-P1C primary antibodies -
Description
FITC Mouse monoclonal [PK136] to NKR-P1C -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
This antibody is specific to Mouse NKR-P1C alloantigen, Mr 80-85 kDa (39 kDa under reducing conditions). -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to NKR-P1C. CE mouse spleen enriched for NK-1+ cells and bone marrow cells
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Sodium chloride, 0.1% Gelatin, 0.14% Monobasic dihydrogen sodium phosphate -
Concentration information loading... -
Purity
Affinity purified -
Purification notes
Purified from TCS -
Clonality
Monoclonal -
Clone number
PK136 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
Target
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Function
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. -
Tissue specificity
Expressed in natural killer cells. -
Sequence similarities
Contains 1 C-type lectin domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 17059 Mouse
- SwissProt: P27814 Mouse
- Unigene: 480764 Mouse
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Alternative names
- CD161 antigen like family member C antibody
- CD161 antigen-like family member C antibody
- CD161c antibody
see all
References (5)
ab25026 has been referenced in 5 publications.
- McAllister CS et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol 190:418-27 (2013). ICC/IF . PubMed: 23209324
- Karlhofer FM & Yokoyama WM Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J Immunol 146:3662-73 (1991). PubMed: 2026886
- Sentman CL et al. Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma 8:605-14 (1989). PubMed: 2613267
- Koo GC et al. The NK-1.1(-) mouse: a model to study differentiation of murine NK cells. J Immunol 137:3742-7 (1986). PubMed: 3782794
- Koo GC & Peppard JR Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma 3:301-3 (1984). PubMed: 6500587
