FITC Anti-NKR-P1C antibody [PK136] (ab25026)
Key features and details
- FITC Mouse monoclonal [PK136] to NKR-P1C
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
FITC Anti-NKR-P1C antibody [PK136]
See all NKR-P1C primary antibodies -
Description
FITC Mouse monoclonal [PK136] to NKR-P1C -
Host species
Mouse -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Specificity
This antibody is specific to Mouse NKR-P1C alloantigen, Mr 80-85 kDa (39 kDa under reducing conditions). -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to NKR-P1C. CE mouse spleen enriched for NK-1+ cells and bone marrow cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Sodium chloride, 0.1% Gelatin, 0.14% Monobasic dihydrogen sodium phosphate -
Concentration information loading... -
Purity
Affinity purified -
Purification notes
Purified from TCS -
Clonality
Monoclonal -
Clone number
PK136 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25026 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
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| Notes |
|---|
|
Flow Cyt
Use at an assay dependent concentration. |
Target
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Function
Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production. -
Tissue specificity
Expressed in natural killer cells. -
Sequence similarities
Contains 1 C-type lectin domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 17059 Mouse
- SwissProt: P27814 Mouse
- Unigene: 480764 Mouse
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Alternative names
- CD161 antigen like family member C antibody
- CD161 antigen-like family member C antibody
- CD161c antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab25026 has been referenced in 6 publications.
- Kimball AS et al. The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. Immunity 51:258-271.e5 (2019). PubMed: 31350176
- McAllister CS et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol 190:418-27 (2013). ICC/IF . PubMed: 23209324
- Karlhofer FM & Yokoyama WM Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. J Immunol 146:3662-73 (1991). PubMed: 2026886
- Sentman CL et al. Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma 8:605-14 (1989). PubMed: 2613267
- Koo GC et al. The NK-1.1(-) mouse: a model to study differentiation of murine NK cells. J Immunol 137:3742-7 (1986). PubMed: 3782794
- Koo GC & Peppard JR Establishment of monoclonal anti-Nk-1.1 antibody. Hybridoma 3:301-3 (1984). PubMed: 6500587