Key features and details
- FITC Rat monoclonal [9D1] to SLAM / CD150
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Product nameFITC Anti-SLAM / CD150 antibody [9D1]
See all SLAM / CD150 primary antibodies
DescriptionFITC Rat monoclonal [9D1] to SLAM / CD150
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Mouse
CHO cells stably transfected with Mouse SLAM/ CD150.
- Mouse thymic and splenic cell suspensions
Mouse hematopoietic stem cells (HSC) can be identified using SLAM/CD150 family markers, such as CD150+CD244-CD48.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS
Concentration information loading...
PurityProtein G purified
Primary antibody notesMouse hematopoietic stem cells (HSC) can be identified using SLAM/CD150 family markers, such as CD150+CD244-CD48.
Our Abpromise guarantee covers the use of ab93527 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.
Use at a concentration of 0.5 - 1 µg/test in a 100µl volume.
FunctionHigh-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Tissue specificityConstitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation.
Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
DomainThe most membrane-proximal SH2-binding motif interacts with SH2 domain of SH2D1A and does not need to be phosphorylated on tyrosine residues.
modificationsPhosphorylated by FYN.
Cellular localizationCell membrane. Present on the surface of B-cells and T-cells.
- Information by UniProt
- 4933415F16 antibody
- AA177906 antibody
- CD 150 antibody
ab93527 has not yet been referenced specifically in any publications.