FITC Anti-Staphylococcus aureus antibody (ab68950)

Submit a review Q&A (1)References (2)

Key features and details

  • FITC Rabbit polyclonal to Staphylococcus aureus
  • Suitable for: ICC/IF, IHC-Fr
  • Reacts with: Staphylococcus aureus
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG

Overview

  • Product name

    FITC Anti-Staphylococcus aureus antibody
    See all Staphylococcus aureus primary antibodies

  • Description

    FITC Rabbit polyclonal to Staphylococcus aureus

  • Host species

    Rabbit

  • Conjugation

    FITC. Ex: 493nm, Em: 528nm

  • Tested applications

    Suitable for: ICC/IF, IHC-Frmore details

  • Species reactivity

    Reacts with: Staphylococcus aureus

  • Immunogen

    Soluble and structural antigens of Staphylococcus aureus whole bacterium; ATCC #27660.

  • General notes


    This antibody reacts with Staphylococcus aureus in bacterial and infected tissue samples.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Associated products

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab68950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
1/10.
IHC-Fr
1/10.
Notes
ICC/IF
1/10.
IHC-Fr
1/10.

Target

  • Relevance

    S.aureus binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.

  • Cellular localization

    Secreted; cell wall.

  • Database links

    • Alternative names

      • IgG binding protein A antibody
      • Immunoglobulin G binding protein A antibody
      • SPA antibody

    References (2)

    Publishing research using ab68950? Please let us know so that we can cite the reference in this datasheet.

    ab68950 has been referenced in 2 publications.

    • Geiger SS  et al. Daily variation in macrophage phagocytosis is clock-independent and dispensable for cytokine production. Immunology 157:122-136 (2019). PubMed: 30773630
    • Becerra SC  et al. An optimized staining technique for the detection of Gram positive and Gram negative bacteria within tissue. BMC Res Notes 9:216 (2016). PubMed: 27071769

    Customer reviews and Q&As

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    Submit a review Submit a question

    Question

    Good afternoon.
    Do you have any answer?

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    Answer

    Thank you for contacting us.

    Please find below the information I managed to collect by contacting the sources of the Anti-Staphylococcus aureusand the Anti-Streptococcus agalactiaeantibodies we have in our catalog :

    Anti-Staphylococcus aureus:
    https://www.abcam.com/ab23568 shows no reactivity to any streptococcus sp., mycoplasma sp. or corynebacteria sp.

    Unfortunately, ab35192 has not been specifically tested against streptococcus so we are unable to guarantee it won’t react to S. agalactiae.

    ab68950, ab68952, ab68954: These Staphylococcus aureus polyclonal antibodies are not absorbed for related microorganisms and so therefore could cross react with related bacteria such as Staph. Epidermidis.

    MLS : Staphylococcus aureus: We do not have an antibody that is specific to Staph. aureus but does not have crossreactivity to Staph. epidermidis.

    Anti-Streptococcus agalactiae:
    https://www.abcam.com/ab21126 has weak crossreactivity with Strep. dysgalactiae and does not cross-react with Strep. uberis, Strep. bovis, Strep. faecalis, Staph. aureus, Mycoplasma bovis, Mycoplasma californicum, Mycoplasma bovigenitalium, E. coli or Corynebacterium bovis.

    I hope this information is helpful to you. I am still waiting for more information about ab128711 (Anti-Streptococcus agalactiae antibody [224/46]).
    Please do not hesitate to contact us if you need any more advice or information.

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