FITC Anti-Staphylococcus aureus antibody (ab68950)
Key features and details
- FITC Rabbit polyclonal to Staphylococcus aureus
- Suitable for: ICC/IF, IHC-Fr
- Reacts with: Staphylococcus aureus
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Overview
-
Product name
FITC Anti-Staphylococcus aureus antibody
See all Staphylococcus aureus primary antibodies -
Description
FITC Rabbit polyclonal to Staphylococcus aureus -
Host species
Rabbit -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: ICC/IF, IHC-Frmore details -
Species reactivity
Reacts with: Staphylococcus aureus -
Immunogen
Tissue, cells or virus corresponding to Staphylococcus aureus. Soluble and structural antigens of Staphylococcus aureus whole bacterium; ATCC #27660.
-
General notes
This antibody reacts with Staphylococcus aureus in bacterial and infected tissue samples.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.1% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
-
Purity
Proprietary Purification -
Primary antibody notes
This antibody reacts with Staphylococcus aureus in bacterial and infected tissue samples. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab68950 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
1/10.
|
|
IHC-Fr |
1/10.
|
Notes |
---|
ICC/IF
1/10. |
IHC-Fr
1/10. |
Target
-
Relevance
S.aureus binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology. -
Cellular localization
Secreted; cell wall. -
Database links
- Entrez Gene: 3919448 Staphylococcus aureus
- SwissProt: P02976 Staphylococcus aureus
-
Alternative names
- IgG binding protein A antibody
- Immunoglobulin G binding protein A antibody
- SPA antibody
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (3)
ab68950 has been referenced in 3 publications.
- Geiger SS et al. Daily variation in macrophage phagocytosis is clock-independent and dispensable for cytokine production. Immunology 157:122-136 (2019). PubMed: 30773630
- Moriwaki M et al. Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL-1α secretion via TLR9. Allergy 74:560-571 (2019). PubMed: 30269350
- Becerra SC et al. An optimized staining technique for the detection of Gram positive and Gram negative bacteria within tissue. BMC Res Notes 9:216 (2016). PubMed: 27071769