FITC Anti-Streptococcus group A antibody (ab68879)

Submit a review Q&A (1)References (2)

Key features and details

  • FITC Rabbit polyclonal to Streptococcus group A
  • Suitable for: ICC/IF, ELISA
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG

Overview

  • Product name

    FITC Anti-Streptococcus group A antibody
    See all Streptococcus group A primary antibodies

  • Description

    FITC Rabbit polyclonal to Streptococcus group A

  • Host species

    Rabbit

  • Conjugation

    FITC. Ex: 493nm, Em: 528nm

  • Specificity

    ab68879 reacts with Streptococcus Group A.

  • Tested applications

    Suitable for: ICC/IF, ELISAmore details

  • Species reactivity

    Reacts with: Other species

  • Immunogen

    Type specific carbohydrate of group A Streptococcus

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C.

  • Storage buffer

    pH: 7.2
    Preservative: 0.1% Sodium azide
    Constituents: 1% BSA, PBS
  • Concentration information loading...

  • Purity

    Protein A purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab68879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/10.
ELISA Use at an assay dependent dilution.

Target

  • Relevance

    The genus Streptococcus is comprised of a wide variety of both pathogenic and commensal gram positive bacteria which are found to inhabit a wide range of hosts, including humans, horses, pigs and cows. Within the host, streptococci are often found to colonize the mucosal surfaces of the mouth, nose and pharynx. Streptococci can be divided into many groups on the basis of antigenic differences in group-specific polysaccharides located in the bacterial cell wall. More than 20 serologic groups have been identified and designated by letters, eg, A, B, C. Group A streptococci, cause a wide-range of disease in humans, from mild sore throats to life-threatening invasive disease such as necrotising fasciitis. Streptococcus pyogenes (a group A Streptococcus) is one of the most important pathogens encountered in clinical practice. Group A streptococci (GAS) are gram-positive, nonmotile, non-spore-forming organisms that appear as pairs or short-to-moderate-sized chains. Group A organisms can be identified by enzyme immunoassays.

  • Alternative names

    • Group A strep antibody
    • Group A streptococci antibody
    • Group A streptococcus antibody

References (2)

Publishing research using ab68879? Please let us know so that we can cite the reference in this datasheet.

ab68879 has been referenced in 2 publications.

  • Cheng YL  et al. Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus. MBio 8:N/A (2017). PubMed: 28743815
  • Lynskey NN  et al. Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction. PLoS Pathog 11:e1005137 (2015). PubMed: 26352587

Customer reviews and Q&As

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Question

ab25870
Please confirm which strain of Strep group A this was raised against.
Please provide a list of the strains in which other Strep group A antibodies have been tested.
Using WB and in vivo.

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Answer

Thank you for your recent telephone enquiry.

I am sorry it has taken some time ot obtain the required information for you as I had quite a few people to contact to gather the details.

I obtained information on the following Strep group A antibodies that have been tested in western blot. As discussed on the telephone, I am sorry to confirm that these will not have been tested in vivo.

ab20509 Positive for Group A (ATCC 10403), Negative for Group B, Group C, Group D, Group F, Group G, S. aureus, Treponema reiter, Neisseria perf., Streptococcus pneumonia mix (8 strains), Bacillus cereus and human cells.
https://www.abcam.com/index.html?datasheet=20509 (or use the following: https://www.abcam.com/index.html?datasheet=20509).

ab20752 Positive for Group A (ATCC 10403), Negative for Group B, Group C, Group D, Group F, Group G, S. aureus, Treponema reiter, Neisseria perf., Streptococcus pneumonia mix (8 strains), Bacillus cereus and human cells.
https://www.abcam.com/index.html?datasheet=20752 (or use the following: https://www.abcam.com/index.html?datasheet=20752).

ab20915 Positive for Streptococcus pyogenes (ATCC 12344, UV-inactivated), Negative for Group B: Type 1a (ATCC 12400), Type 1b (ATCC 12401), Type 1c (ATCC 27591), Type II (ATCC 12973) and Type III (ATCC 12403); Group C = ATCC 12960; Group D = ATCC 12389; Group E = ATCC 12390, Group F = ATCC 12393 & Group G = ATCC 27961.
https://www.abcam.com/index.html?datasheet=20915 (or use the following: https://www.abcam.com/index.html?datasheet=20915).


ab21034 Positive for Group A (ATCC 10403), Negative for Group B, Group C, Group D, Group F, Group G, S. aureus, Treponema reiter, Neisseria perf., Streptococcus pneumonia mix (8 strains), Bacillus cereus and human cells.
https://www.abcam.com/index.html?datasheet=21034 (or use the following: https://www.abcam.com/index.html?datasheet=21034).

ab21046 Positive for Group A (ATCC 10403), Negative for Group B, Group C, Group D, Group F, Group G, S. aureus, Treponema reiter, Neisseria perf., Streptococcus pneumonia mix (8 strains), Bacillus cereus and human cells.
https://www.abcam.com/index.html?datasheet=21046 (or use the following: https://www.abcam.com/index.html?datasheet=21046).

ab25870 Specific for Group A carbohydrate.
https://www.abcam.com/index.html?datasheet=25870 (or use the following: https://www.abcam.com/index.html?datasheet=25870).


ab36303 Anti-Streptococcus group A antibody [5A1]
https://www.abcam.com/index.html?datasheet=36303 (or use the following: https://www.abcam.com/index.html?datasheet=36303).
This antibody was tested and found positive against the following:
a. Group A Streptococcus = Streptococcus pyogenes, ATCC #12344

2. The antibody was tested and found negative against the following:

a. Group B Streptococcus = Type Ia (ATCC # 12400), Type Ib (ATCC # 12401), Type Ic (ATCC #27591), Type II (ATCC # 12973), and Type III (ATCC# 12403)

b. Group C Streptococcus = ATCC # 12960

c. Group D Streptococcus = ATCC #12389

d. Group E Streptococcus = ATCC # 12390

e. Group F Streptococcus = ATCC #12393

f. Group G Streptococcus = ATCC #27961


ab68879 ab68880 ab68881 have been specifically tested for reactivity against the ATCC 10403 strain of Group A Streptococcus. It was also tested and found to be negative against Treponema ryder, S. pneumoniae, and Streptococcus Group B, C, D, F, and G.
https://www.abcam.com/index.html?datasheet=68879 (or use the following: https://www.abcam.com/index.html?datasheet=68879).
https://www.abcam.com/index.html?datasheet=68880 (or use the following: https://www.abcam.com/index.html?datasheet=68880).
https://www.abcam.com/index.html?datasheet=68881 (or use the following: https://www.abcam.com/index.html?datasheet=68881).

I hope this information will be helpful. If you have any further questions, please do not hesitate to contact me.

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