Key features and details
- FITC Mouse monoclonal [R73] to TCR alpha + TCR beta
- Reacts with: Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Product nameFITC Anti-TCR alpha + TCR beta antibody [R73]
See all TCR alpha + TCR beta primary antibodies
DescriptionFITC Mouse monoclonal [R73] to TCR alpha + TCR beta
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab176542 recognizes TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
Species reactivityReacts with: Rat
Predicted to work with: Non human primates
Tissue, cells or virus corresponding to Rat TCR alpha + TCR beta. Rat T blasts and erythrocytes.
Database link: 24820
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.40
Preservative: 0.098% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Purification notesThis conjugate is made from a highly purified antibody (>95% by SDS-PAGE); free of unconjugated FITC.
RelevanceThe receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
Cellular localizationType I membrane protein.
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ab176542 has not yet been referenced specifically in any publications.