Key features and details
- FITC Armenian hamster monoclonal [GL3] to TCR gamma + TCR delta
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameFITC Anti-TCR gamma + TCR delta antibody [GL3]
See all TCR gamma + TCR delta primary antibodies
DescriptionFITC Armenian hamster monoclonal [GL3] to TCR gamma + TCR delta
Host speciesArmenian hamster
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab118864 antibody reacts with the surface on all TCR gamma + TCR delta bearing cells and does not react with receptors on alpha beta TCR positive cells.
Species reactivityReacts with: Mouse
ab118864 was raised against Mouse C57BL/6 intraepithelial lymphocytes.
- Mouse spleen tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Constituents: 99% PBS, 0.5% BSA
EIA grade BSA
Concentration information loading...
PurityProtein G purified
RelevanceT cell receptors (TCR) recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one a and one b chain or one d and one g chain. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. The g/d TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most g/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the g/d TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease.
Cellular localizationType I membrane protein
- CD_antigen=CD3d antibody
- CD3D antibody
- CD3G antibody
ab118864 has been referenced in 2 publications.
- Liu M et al. ?dT Cells Suppress Liver Fibrosis via Strong Cytolysis and Enhanced NK Cell-Mediated Cytotoxicity Against Hepatic Stellate Cells. Front Immunol 10:477 (2019). PubMed: 30930903
- Zhao Y et al. Myeloid-Derived Suppressor Cells and ?dT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice. Front Immunol 10:3104 (2019). PubMed: 32063899