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Microbiology Organism Virus DNA Virus double stranded DNA Virus HHV
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FITC Anti-Varicella Zoster Virus antibody [5B7] (ab128768)

  • Datasheet
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Abpromise

Guaranteed product quality, expert customer support.

Find out more.

Key features and details

  • FITC Mouse monoclonal [5B7] to Varicella Zoster Virus
  • Suitable for: ICC/IF
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgM

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Overview

  • Product name

    FITC Anti-Varicella Zoster Virus antibody [5B7]
    See all Varicella Zoster Virus primary antibodies
  • Description

    FITC Mouse monoclonal [5B7] to Varicella Zoster Virus
  • Host species

    Mouse
  • Conjugation

    FITC. Ex: 493nm, Em: 528nm
  • Specificity

    ab128768 is specific for Varicella zoster virus. It does not cross react with HSV1, 2 or CMV.
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Varicella zoster virus, Ellen strain (P09258; P09259; P09260).

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store undiluted. The product can be stored for up to 12 months.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 1% BSA, 98% PBS
  • Concentration information loading...
  • Purity

    Purified IgM
  • Clonality

    Monoclonal
  • Clone number

    5B7
  • Isotype

    IgM
  • Research areas

    • Microbiology
    • Organism
    • Virus
    • DNA Virus
    • double stranded DNA Virus
    • HHV
    • Microbiology
    • Organism
    • Virus
    • DNA Virus
    • double stranded DNA Virus
    • Other dsDNA viruses

Associated products

  • Isotype control

    • FITC Mouse IgM [B11/7] - Isotype Control (ab91546)

Applications

Our Abpromise guarantee covers the use of ab128768 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent dilution.

Target

  • Relevance

    Varicella Zoster Virus (VZV), a member of the human herpes virus family, causes two distinct clinical manifestations: childhood chickenpox(Varicella) and shingles (zoster). Varicella is the outcome of the primary infection with VZV, whereas, zoster is the result of VZV reactivation from latently infected sensory ganglia which occurs predominantly in aging and immunosuppressed individuals. VZV is closely related to the herpes simplex viruses (HSV), sharing much genome homology. The known envelope glycoproteins (gB, gC, gE, gH, gI, gK, gL) correspond with those in HSV, however there is no equivalent of HSV gD. VZV virons are spherical and 150-200 nm in diameter. Its lipid envelope encloses the nucleocapsid of 162 capsomeres arranged in a hexagonal form. Its DNA is a single linear, double strand molecule, 125,000 nt long. Glycoprotein E (gE), a 623 amino acid type I integral membrane protein, is expressed on plasma membranes and in the cytoplasm of VZV infected cells, where it is presumed to be present in the membranes of intracellular vesicles or organelles. VZV gE complexes with gI in the rough endoplasmic reticulum, and most gE exists in the form of gE to gI heterodimers in infected cells. VZV gE is also a predominant component of the virion envelope. The functions of gE, which is encoded by ORF68, are of particular interest because it has been demonstrated that ORF68 is essential for VZV replication. In contrast, the genes for gE proteins can be deleted from herpes simplex virus and pseudorabies virus, albeit with significant reductions in infectivity in cell culture and in animal models. Since the VZV genome does not encode a homologue of gD, VZV gE may have functions that are usually segregated between gD and gE, or the gE to gI complex, in other alphaherpesviruses.
  • Alternative names

    • HHV3 antibody
    • Human herpes virus 3 antibody
    • Varicella Zoster Virus antibody
    • VZV antibody

Protocols

  • Immunocytochemistry & immunofluorescence protocols

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab128768? Please let us know so that we can cite the reference in this datasheet.

    ab128768 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
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    1-2 of 2 Abreviews or Q&A

    Immunocytochemistry/ Immunofluorescence abreview for Anti-Varicella Zoster Virus antibody [5B7] (FITC)

    Poor
    Abreviews
    Abreviews
    abreview image
    Application
    Immunocytochemistry/ Immunofluorescence
    Blocking step
    Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Sample
    Human Cell (Human Fetal Lung Fibroblasts)
    Specification
    Human Fetal Lung Fibroblasts
    Permeabilization
    Yes - 0.3% Triton in PBS, 10 min, Room Temp
    Fixative
    Formaldehyde
    Read More

    Abcam user community

    Verified customer

    Submitted Jun 24 2014

    Flow Cytometry abreview for Anti-Varicella Zoster Virus antibody [5B7] (FITC)

    Poor
    Abreviews
    Abreviews
    abreview image
    Application
    Flow Cytometry
    Fixation
    Formaldehyde
    Sample
    Human Cell (Human Fetal Lung Fibroblast)
    Specification
    Human Fetal Lung Fibroblast
    Permeabilization
    Yes - BD perm kit
    Read More

    Abcam user community

    Verified customer

    Submitted Jun 20 2014

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