Product nameFKBP38 peptide
Our Abpromise guarantee covers the use of ab51928 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Thimerosal (merthiolate)
Constituents: 0.1% BSA, PBS
- 38 kDa FK506-binding protein
- 38 kDa FKBP
FunctionConstitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Tissue specificityWidely expressed. Highest levels seen in the brain.
Sequence similaritiesContains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats.
Cellular localizationMitochondrion membrane.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab51928 has not yet been referenced specifically in any publications.