Product nameAnti-FKBP6 antibody [EPR3673]
See all FKBP6 primary antibodies
DescriptionRabbit monoclonal [EPR3673] to FKBP6
Tested applicationsSuitable for: WB, IHC-P, Flow Cytmore details
Unsuitable for: ICC or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human FKBP6 (internal sequence). The exact sequence is proprietary.
- Recombinant human FKBP6 protein (ab95497) can be used as a positive control in WB. Molt-4, Saos-2, 293T and Human heart lysates; Human breast tissue
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol, 9.85% Tris glycine, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab108419 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/50000 - 1/200000. Predicted molecular weight: 38 kDa.|
|IHC-P||1/100 - 1/250. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|Flow Cyt||1/100 - 1/500.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
FunctionPPIases accelerate the folding of proteins.
Tissue specificityDetected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
Involvement in diseaseNote=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Sequence similaritiesContains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats.
- Information by UniProt
- 36 kDa FK506 binding protein antibody
- 36 kDa FK506-binding protein antibody
- 36 kDa FKBP antibody
All lanes : Anti-FKBP6 antibody [EPR3673] (ab108419) at 1/50000 dilution
Lane 1 : Molt-4 cell lysate
Lane 2 : Saos-2 cell lysate
Lane 3 : 293T cell lysate
Lane 4 : Human heart lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 38 kDa
ab108419, at 1/100 dilution, staining FKBP6 in paraffin-embedded Human breast tissue by Immunohistochemistry.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.