Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3674] to FKBP6
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
Product nameAnti-FKBP6 antibody [EPR3674]
See all FKBP6 primary antibodies
DescriptionRabbit monoclonal [EPR3674] to FKBP6
Tested applicationsSuitable for: WB, IHC-Pmore details
Unsuitable for: ICC/IF or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human FKBP6 aa 250-350 (C terminal). The exact sequence is proprietary.
- Molt-4 and SAOS-2 cell lysates. Human tonsil tissue.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab92475 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/100 - 1/250 antigen retrieval is recommended.
WB: 1/1000 - 1/10000. Detects a band of approximately 38 kDa (predicted molecular weight: 37 kDa).
Is unsuitable for ICC/IF or IP.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionPPIases accelerate the folding of proteins.
Tissue specificityDetected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
Involvement in diseaseNote=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Sequence similaritiesContains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats.
- Information by UniProt
- 36 kDa FK506 binding protein antibody
- 36 kDa FK506-binding protein antibody
- 36 kDa FKBP antibody
All lanes : Anti-FKBP6 antibody [EPR3674] (ab92475) at 1/1000 dilution
Lane 1 : Molt-4 cell lysate
Lane 2 : SAOS-2 cell lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit antibody at 1/2000 dilution
Predicted band size: 37 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
Ab92475 at 1/100 dilution staining FKBP6 in paraffin-embedded Human tonsil tissue, by immunohistochemistry.
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ab92475 has not yet been referenced specifically in any publications.