• Product name

    Anti-FKLF / KLF11 antibody [KLF5J027]
    See all FKLF / KLF11 primary antibodies
  • Description

    Mouse monoclonal [KLF5J027] to FKLF / KLF11
  • Host species

  • Tested applications

    Suitable for: Dot blot, WBmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant Human KLF11



Our Abpromise guarantee covers the use of ab50780 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Detects a band of approximately 37 kDa (predicted molecular weight: 56 kDa).


  • Function

    Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.
  • Tissue specificity

    Ubiquitous. Higher expression in erythroid cells.
  • Involvement in disease

    Defects in KLF11 are the cause of maturity-onset diabetes of the young type 7 (MODY7) [MIM:610508]. MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.
  • Sequence similarities

    Belongs to the Sp1 C2H2-type zinc-finger protein family.
    Contains 3 C2H2-type zinc fingers.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • 9830142A17 antibody
    • D12Ertd427e antibody
    • FKLF antibody
    • FKLF1 antibody
    • Klf11 antibody
    • KLF11_HUMAN antibody
    • Krueppel like factor 11 antibody
    • Krueppel-like factor 11 antibody
    • Krueppel-like transcription factor 1 antibody
    • MODY7 antibody
    • Tcfcp2l2 antibody
    • TGFB Early Growth Response 2 antibody
    • TGFB-inducible early growth response protein 2 antibody
    • TGFB-inducible early growth response protein 2b antibody
    • TGFB-inducible early growth response protein 3 antibody
    • TIEG 2 antibody
    • TIEG-2 antibody
    • TIEG-3 antibody
    • Tieg2b antibody
    • Transforming Growth Factor Beta Inducible Early Growth Response 2 antibody
    • Transforming growth factor-beta-inducible early growth response protein 2 antibody
    • Transforming growth factor-beta-inducible early growth response protein 3 antibody
    see all


  • Anti-FKLF / KLF11 antibody [KLF5J027] (ab50780) + Immunizing recombinant protein

    Predicted band size: 56 kDa
    Observed band size: 37 kDa
    why is the actual band size different from the predicted?

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.


ab50780 has not yet been referenced specifically in any publications.

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