Anti-Flt3 / CD135 antibody (ab150599)
Key features and details
- Rabbit polyclonal to Flt3 / CD135
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-Flt3 / CD135 antibody
See all Flt3 / CD135 primary antibodies -
Description
Rabbit polyclonal to Flt3 / CD135 -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rabbit, Horse, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Common marmoset, Bat, Elephant -
Immunogen
Synthetic peptide corresponding to Human Flt3/ CD135 (C terminal). A synthetic 18 amino acid peptide corresponding to residues surrounding the C-terminal of Human FLT3/ CD135 (NP_004110.2).
-
Positive control
- Human tonsil tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150599 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
Notes |
---|
IHC-P
Use a concentration of 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
-
Function
Receptor for the FL cytokine. Has a tyrosine-protein kinase activity. -
Tissue specificity
Bone marrow cells. -
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 486025 Dog
- Entrez Gene: 2322 Human
- Entrez Gene: 14255 Mouse
- Omim: 136351 Human
- SwissProt: P36888 Human
- SwissProt: Q00342 Mouse
- Unigene: 507590 Human
- Unigene: 194 Mouse
-
Alternative names
- CD 135 antibody
- CD135 antibody
- CD135 antigen antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab150599 has been referenced in 2 publications.
- Harding K et al. C-kit, flt-3, PDGFR-β, and VEGFR2 expression in canine adrenal tumors and correlation with outcome following adrenalectomy. Can J Vet Res 85:279-284 (2021). PubMed: 34602732
- Bangi E et al. A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer. Sci Adv 5:eaav6528 (2019). PubMed: 31131321