Fluo-3 AM, Fluorescent calcium Indicator (ab145254)
Key features and details
- Cell-permeable fluorescent calcium Indicator.
- CAS Number: 121714-22-5
- Purity: > 95%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Fluo-3 AM, Fluorescent calcium Indicator -
Description
Cell-permeable fluorescent calcium Indicator. -
Alternative names
- 1-[2-Amino-5-(2,7-dichloro-6-hydroxy-3-oxo-9-xanthenyl)phenoxy]-2-(2-amino-5-methylphenoxy)ethane-N,N,N',N'-tetraacetic acid, pentaacetoxymethyl ester
- Fluo-3 acetoxymethyl ester
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Purity
> 95% -
CAS Number
121714-22-5 -
Chemical structure
Properties
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Excitation
506nm -
Emission
526nm -
Molecular weight
1129.85 -
Molecular formula
C51H50Cl2N2O23 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
For more information on AM esters please visit our AM esters FAQ page.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab145254 has been referenced in 6 publications.
- Chen TT et al. Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway. Aging (Albany NY) 13:9542-9565 (2021). PubMed: 33714957
- Fu Z et al. Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor. Clin Sci (Lond) 135:793-810 (2021). PubMed: 33625485
- Zhang F et al. Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion. Nat Commun 11:1822 (2020). PubMed: 32286278
- Chi X et al. Protective Effect of Epigallocatechin-3-Gallate in Hydrogen Peroxide-Induced Oxidative Damage in Chicken Lymphocytes. Oxid Med Cell Longev 2020:7386239 (2020). PubMed: 33488931
- Chen Y et al. Baicalein inhibits fibronectin-induced epithelial-mesenchymal transition by decreasing activation and upregulation of calpain-2. Cell Death Dis 10:341 (2019). PubMed: 31000696
- Yuan H et al. Calcium-sensing receptor promotes high glucose-induced myocardial fibrosis via upregulation of the TGF-ß1/Smads pathway in cardiac fibroblasts. Mol Med Rep 20:1093-1102 (2019). PubMed: 31173208