Fluorometholone acetate, Synthetic corticosteroid (ab145831)

Overview

  • Product name

    Fluorometholone acetate, Synthetic corticosteroid
  • Description

    Synthetic corticosteroid
  • Alternative names

    • Flarex
    • Fluorometholone 17-acetate
    • FMT
    • NSC 47438
    • Oxylone acetate
    see all
  • Biological description

    Synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

  • Purity

    > 99%
  • CAS Number

    3801-06-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(6S,8S,9R,10S,11S,13S,14S,17R)-17-Acetyl-9-fluoro-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate
  • Molecular weight

    418.50
  • Molecular formula

    C24H31FO5
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Hata Y  et al. Preclinical investigation of fluorometholone acetate as a potential new adjuvant during vitreous surgery. Graefes Arch Clin Exp Ophthalmol 245:1019-25 (2007). Read more (PubMed: 17186258) »
  • Leibowitz HM  et al. Fluorometholone acetate: clinical evaluation in the treatment of external ocular inflammation. Ann Ophthalmol 16:1110-5 (1984). Read more (PubMed: 6398026) »
  • Kupferman A  et al. Fluorometholone acetate. A new ophthalmic derivative of fluorometholone. Arch Ophthalmol 100:640-1 (1982). Read more (PubMed: 7073584) »

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