Overview

  • Product name

    Fluticasone propionate, Glucocorticoid agonist
  • Description

    Potent, selective glucocorticoid agonist
  • Biological description

    Potent, selective glucocorticoid agonist (EC50 = 3.7 nM). Higher affinity for the glucocorticoid receptor compared to beclomethasone (Kd = 0.5 nM). Lipophilic anti-inflammatory agent. Biological effects include eosinophil apoptosis, reduction in mast cell production and inhibition of TNF-α induced endothelial cell adhesion. Active in vivo.
  • Purity

    > 99%
  • CAS Number

    80474-14-2
  • Chemical structure

    Chemical Structure

Properties

References

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